This procedure requires general anesthesia as well as IV fluid therapy, enemas and fasting done at home (24 hours of fluids only) in order to clean the colon out sufficiently. A fiberoptic scope is passed up the colon via the rectum as far as possible to check for polyps, masses or to get biopsies of the lower GI tract. It is sometimes combined with endoscopy to get the most out of the biopsies. The animals are typically admitted in the morning with the procedure being done early afternoon so the animals can go home later in the afternoon.